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Food Intolerance and Inflammation
date added:02/10/2013

For a long time now it has been thought that inflammation is linked to disease. Evidence to support this continues to grow linking systemic inflammation with a seemingly endless list of chronic diseases. These include cancer , arthritis, Alzheimer’s , depression, coeliac disease, auto immune disease, asthma, migraines, obesity and cardiovascular disease. Subsequently inflammation has become the current buzz word in the health industry and one which is very likely to stay.

If, as is currently being muted, disease has its origin in low grade inflammation it follows that reducing it plays a key role in any protocol. Protocols will of course vary from client to client, but the end result will be the same - as inflammation is reduced in the body, vitality and overall health will increase.

There are of course many ways in which to address this chronic low grade inflammation and one of these is food intolerance testing or IgG antibody testing. By identifying which foods clients are reacting to and supporting them in removing these from their diet practitioners are able to go some way towards helping their clients reduce their overall inflammatory load. As the inflammatory response is reduced the body’s natural healing mechanisms are able to operate more effectively.

Testing for total IgG antibodies helps to reduce inflammation as it takes IgG1 and IgG3 antibodies into account, both of which have pro-inflammatory properties. Some of these inflammatory properties are associated with the ability of these antibodies to form antigen-antibody complexes which are then capable of activating the complement cascade. This results in foreign cells being destroyed by phagocytosis and lysis of the cell membrane all of which results in inflammation. By removing foods from the diet which are associated with these raised antibodies the likelihood of triggering this cascade is reduced and subsequently the client’s inflammatory picture can improve.

Research supports this with studies showing how testing for IgG antibodies has helped in improving conditions like obesity , migraines , arthritis and IBS .
The key to health should always start from a preventative viewpoint and if reducing inflammation plays a role in this then that is something that we should aim for. A food IgG test is just one way in which this might be achieved.

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Wilders-Truschnig, M., Mangge, H., Lieners, C., Gruber, H.J., Mayer, C., & Marz, W. (2008). IgG antibodies against food antigens are correlated with Inflammation and intima media thickness in obese juveniles. Experimental and Clinical Endocrinology & Diabetes. 116:241-245.

Alpay, K, Ertas, M, Orhan, E.K., Üstay, D.K., Lieners, C. & Baykan, B. (2010). Diet restriction in migraine, based on IgG against foods: A clinical double-blind, randomised, cross-over trial. Cephalalgia. July;30(7):829-837

Hvatum, M. Kanerud, L. Hallgren, R. & Brandtzaeg. (2006). The gut-joint axis: cross reactive food antibodies in rheumatoid arthritis. Gut, 55:1240-1247
Atkinson, W, Sheldon, T.A., Shaath, N. & Whorwell, P.J. (2004). Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial. Gut. 53: 1459-1464.
 


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